Generally speaking, the safety study of the combination vaccine is compared with the simultaneous vaccination of each monovalent component vaccine in the combined vaccine at different sites. For example, the DTP-HB vaccine is compared with the DTP and HB vaccines separately.
In general, joint vaccine safety studies are compared with each unit-priced vaccine in different parts of the vaccine at the same time, for example, DTP-HB vaccine and DTP and HB vaccines are given separately.
Generally speaking, the safety study of combined vaccine is compared with that of each univalent component vaccine in different parts of the joint vaccine at the same time. For example, DTP-HB vaccine is compared with DTP and HB vaccine respectively.<br>