综合运用基于结构的药物设计和经典药物设计策略，设计合成4个系列60-7

Comprehensive use of structure-based drug design and classic drug design strategies, design and synthesize 4 series of 60-70 new derivatives, and perform virtual screening and physical and chemical properties prediction of the designed compounds.

Using structure-based drug design and classical drug design strategy, the design and synthesis of 4 series of 60-70 new derivatives, and the design of compounds for virtual screening and physical and chemical properties prediction.

Four series of 60-70 new derivatives were designed and synthesized by using structure based drug design and classical drug design strategies, and the virtual screening and physicochemical properties prediction of the designed compounds were carried out.<br>