UCMSC来源的外泌体能够促进成纤维细胞和口腔上皮细胞的迁移和增殖.通

UCMSC-derived exosomes can promote the migration and proliferation of fibroblasts and oral epithelial cells. The wnt signaling pathway that promotes the proliferation of DFLs cells was screened by RNA Seq and verified by qRT-PCR and western-bolt. In vivo experiments also show that exosomes derived from UCMSC can promote tissue healing faster. In addition, in vivo and in vitro experiments have further proved that linker chimeric peptides are more effective in promoting tissue healing than no linker chimeric peptides.

The exosomes from UCMSC sources can promote the migration and proliferation of fibroblasts and oral cortogenic cells. The wnt signal path that promotes the proliferation of DFLs cells was screened by RNA Seq and verified with qRT-PCR and Western-bolt. In vivo experiments have also shown that exosomes from UCMSC sources can promote tissue healing more quickly. In addition, in vivo and in vivo experiments have further demonstrated that linker-embedded peptides promote tissue healing more effectively than non-linker-embedded peptides.

Exosomes derived from ucmsc can promote the migration and proliferation of fibroblasts and oral epithelial cells. Wnt signaling pathway was screened by RNA SEQ and verified by QRT PCR and Western bolt. In vivo experiments also showed that the exosomes from ucmsc could promote tissue healing faster. In addition, in vivo and in vitro experiments further proved that the linker chimeric peptide can promote tissue healing more effectively than no linker chimeric peptide.<br>