两组患者均进行血细胞分析、肝功能、肾功能检查，并对异常指标给予相应纠正

Both groups of patients underwent blood cell analysis, liver function, and renal function tests, and the abnormal indicators were corrected accordingly. <br><br>Hydration the day before chemotherapy, the control group was treated with conventional paclitaxel combined with cisplatin chemotherapy: paclitaxel 75～145mg/m2; cisplatin 25mg/m2 for more than 2h. Tests during chemotherapy, antiemetics, protection of liver and kidney function, and fluid replacement Waiting for treatment, 3 weeks is a course of treatment. <br><br>On the basis of the control group, the experimental group was treated with apatinib mesylate tablets, 500 mg/d, for 3 weeks.

Both groups of patients carried out blood cell analysis, liver function, renal function examination, and the abnormal indicators were corrected accordingly.<br><br>The day before chemotherapy hydration, the control group adopted conventional yew alcohol combined cisplatin chemotherapy program: yew alcohol 75 to 145 mg/m2;<br><br>The experimental group was given a methcarbonate apatini tablet therapy on the basis of the control group, 500 mg/d, for 3 consecutive weeks.

Blood cell analysis, liver function and renal function were performed in both groups, and the abnormal indexes were corrected accordingly.<br>The control group received conventional paclitaxel combined with cisplatin chemotherapy regimen: Paclitaxel 75-145 mg / m2; cisplatin 25 mg / m2, lasting for more than 2 hours. During the chemotherapy, the patients were given the treatment of anti emesis, protection of liver and kidney function, fluid supplement and other treatment, 3 weeks as a course of treatment.<br>On the basis of the control group, the experimental group was given apatinib methylcarbonate tablets, 500mg / D, for 3 weeks.<br>