此外，即使致密性在湿法制粒后失去，微晶纤维素也可以作为制粒助剂在颗粒内

In addition, even if the compactness is lost after wet granulation, microcrystalline cellulose can be added as a granulation aid in the granules, usually in an amount of between 5% and 20%. Granulation and drying process. <br>Its presence within the granules promotes rapid and uniform wetting and drying, which helps avoid excessive granulation during high-shear mixing and soluble colorants (and other (Soluble component) The tendency of uneven distribution is reduced. Efatinib mesylate has certain water solubility, and microcrystalline cellulose is selected as the filler of efatinib mesylate tablets for the purpose of avoiding the tendency of uneven distribution.

In addition, even if the density is lost after wet granules, microcrystalline cellulose can be added within the grain as a granulated additive, usually between 5% and 20%, its hydrophilicity and water retention are conducive to the granulation and drying process.<br>Its presence within the particles facilitates rapid, uniform wetting and drying, which helps to avoid excessive granulation during high shear mixing, as well as a decrease in the uneven distribution of soluble colorants (and other soluble components) due to migration during particle drying. Mesulfonate eflutinib has a certain water solubility, microcrystalline cellulose was selected as a filler for methsulfonate eflutinib tablets in order to avoid the trend of uneven distribution.

In addition, microcrystalline cellulose can also be added into the particles as a granulating agent, even if the density is lost after wet granulation, usually the amount of addition is between 5% and 20%, and its hydrophilicity and water retention are conducive to the granulation and drying process.<br>Its presence in the particles promotes rapid and uniform wetting and drying, which helps to avoid excessive granulation in the process of high shear mixing and the decrease of the uneven distribution of soluble Colorants (and other soluble components) due to the migration in the drying process of particles. The microcrystalline cellulose was selected as the filling agent of efetinib mesylate tablets in order to avoid the uneven distribution trend.