对KD并发CAT的高危因素的探讨，以及超声心动图对KD并发CAT的影像

Discussion on the high-risk factors of KD complicated by CAT, and echocardiographic analysis of the image performance of KD complicated by CAT, so as to predict the possibility of CAT early, which is helpful for risk stratification of children with KD complicated by CAL and avoid serious cardiovascular diseases The occurrence of sequelae of the disease. <br><br>192 children diagnosed with KD and CAL in Z Hospital from January 2012 to December 2018 were selected and divided into CAT group 32 cases, CAA group (excluding CAT) 32 cases and CAD group (excluding CAA and CAT) ) 128 cases. <br><br>Laboratory examination indicators during hospitalization of each child, including white blood cell count, hemoglobin, platelet count, erythrocyte sedimentation rate, and C-reactive protein were collected. At the same time, various measurement indicators of coronary echocardiography were collected: the inner diameter of the left main coronary artery, The inner diameter of the left anterior descending branch, the inner diameter of the left circumflex branch, the inner diameter of the right coronary artery and the size of CAA and CAT. <br><br>The univariate statistical analysis was performed with the results of laboratory examinations and coronary artery ultrasound in the three groups of children. <br>Logistic multiple regression analysis was performed again on statistically significant indicators, high-risk factors that progressed to CAT in KD with CAL were analyzed, and ROC was used to obtain the diagnostic cut-off value of related examinations. <br><br>From the single factor statistical analysis among the three groups, it can be found that the significant statistical difference is not found in the various laboratory tests, but only in the dilated inner diameter of the coronary artery. <br><br>The coronary artery diameter of the CAT group was significantly larger than that of the other two groups. <br><br>Logistic regression analysis results also confirmed that coronary artery dilation is a high risk factor for KD complicated with CAT. <br><br>The area under the ROC curve of the CAT risk prediction model is 0.83, the 95% confidence interval is..., the best diagnostic cut-off value with coronary artery diameter is..., and the corresponding specificity and sensitivity are respectively...and... <br><br>In this study, the locations of CAT occurrence were ranked as follows: left anterior descending coronary artery, left main coronary artery, right coronary artery, left circumflex coronary artery, and coronary sinus. <br><br>Statistics show that the left anterior descending coronary artery is the most prone site for thrombosis, while thrombosis in the left circumflex coronary artery and coronary sinus is relatively rare.<br><br>Some children have multiple CAT, involving multiple coronary arteries at the same time. <br>The average size of thrombus in this group of cases is about..., with the largest one being..., the smallest one being.... <br><br>Coronary angiography and CT angiography in children should not be checked frequently because of the risks. Therefore, transthoracic echocardiography is currently the most important means of CAT detection and follow-up. <br><br>It is worth noting that CAT mainly occurs in children with CAA, but it can also occur in children with CAD. Children with KD and CAL need regular follow-up echocardiography to prevent the occurrence of CAT. <br><br>For children with KD complicated with CAL, the degree of coronary artery dilation is a high risk factor for their progression to CAT, and the maximum diameter of coronary artery dilation... is the critical value. <br><br>CAT is most likely to occur in the left anterior descending coronary artery, followed by the left main coronary artery, which may be related to the hemodynamics of the left coronary artery.

The study of the high-risk factors of KD-associated CAT, as well as the analysis of the image performance of KD-2CAT by echo cardiac chart, in order to predict the possibility of CAT occurrence at an early stage, is conducive to the dangerous stratation of children with KD-2CAL and avoid the occurrence of severe cardiovascular disease sequelae.<br><br>From January 2012 to December 2018, 192 children diagnosed with KD-linked CAL were selected at Z Hospital, divided into 32 cases in CAT group, 32 cases in CAA group (excluding CAT) and 128 cases in CAD group (excluding CAA and CAT).<br><br>Laboratory test indicators for each child's hospitalization included white blood cell count, hemoglobin, plate plate count, red blood cell sedation rate, C reaction protein was collected, and measurements of coronary artery echo cardiogram were collected: left coronary artery aortic aortic atherosclerosis internal diameter, left frontal degeneration inner diameter, left gyrocyte internal diameter, right coronary artery internal diameter and CAA, CAT size.<br><br>Single-factor statistical analysis carried out laboratory examination and coronary artery ultrasound on three groups of children.<br>Logistic multi-regression analysis is re-ed to statistically significant indicators, high-risk factors that progress to CAT in KD-parallel CAL are analyzed, and ROCs are used to arrive at diagnostic thresholds for related examinations.<br><br>From the single-factor statistical analysis between the three groups, it can be found that the significant statistical differences are not visible in various laboratory examinations, but only in the coronary artery dilation inner diameter.<br><br>The coronary artery inner diameter of the CAT group was significantly larger than that of the other two groups.<br><br>Logistic regression analysis results also confirmed that the coronary artery dilated inner diameter is a high risk factor for KD-symped CAT.<br><br>Cat risk prediction model ROC curve area of 0.83, 95% confidence interval is ..., with coronary artery internal diameter of the best diagnostic threshold is ..., the corresponding specificity and sensitivity are ... And.......<br><br>In this study, the CAT occurrence site was arranged according to the occurrence rate: left coronary artery pre-descending, left coronary artery trunk, right coronary artery, coronary artery left spin branch and coronary sinuses.<br><br>Statistical results show that the left coronary artery pre-descending is the most prone to thrombosis, while the coronary artery left branch and coronary sinuses appear thrombosis is relatively rare.<br><br>Some children have multiple CAT and multiple coronary arteries.<br>The average size of blood clots in this group is about... with the largest and smallest...<br><br>Coronary angiosis and CT angioscopy in children should not be examined frequently because of the risks that may arise. Therefore, by chest echo echo heart map examination is currently the most important CAT detection and follow-up means.<br><br>It is important to note that CAT occurs mainly in children with CAA, but can also occur in children with CAD. Children with KD-and-CAL need to follow up with echo cardiac charts regularly to prevent CAT from occurring.<br><br>For children with KD-and-CAL, coronary artery dilation is a high-risk factor for its progression to CAT, and coronary artery dilation has the largest internal diameter... is a critical value.<br><br>CAT is most likely to occur in the front of the left coronary artery, followed by the left coronary artery trunk, which may be related to the blood flow of the left coronary artery.

To explore the high-risk factors of KD complicated with cat, and to analyze the imaging manifestations of KD complicated with cat by echocardiography, so as to predict the possibility of cat early, which is conducive to the risk stratification of KD complicated with CAL, and to avoid the occurrence of serious cardiovascular disease sequelae.<br>From January 2012 to December 2018, 192 children diagnosed with KD complicated with CAL in Z hospital were selected and divided into Cat group (32 cases), CAA group (excluding cat) 32 cases and CAD group (excluding CAA and cat) 128 cases.<br>The laboratory examination indexes including white blood cell count, hemoglobin, platelet count, erythrocyte sedimentation rate and C-reactive protein were collected. At the same time, the measurement indexes of coronary echocardiography were collected: the diameter of left main coronary artery, the diameter of left anterior descending artery, the diameter of left circumflex artery, the diameter of right coronary artery and the size of CAA and cat.<br>Univariate statistical analysis was used to analyze the results of laboratory examination and coronary artery ultrasound.<br>Logistic multiple regression analysis was performed for statistically significant indicators. The high-risk factors for developing cat in KD complicated with cal were analyzed. ROC was used to obtain the diagnostic threshold of relevant examinations.<br>From the univariate statistical analysis among the three groups, significant statistical differences could not be found in various laboratory tests, but only in the diameter of coronary artery dilatation.<br>The coronary artery diameter of cat group was significantly larger than that of the other two groups.<br>Logistic regression analysis also confirmed that the diameter of coronary artery dilatation was the high risk factor of KD complicated with cat.<br>The area under the ROC curve of cat risk prediction model is 0.83, and the 95% confidence interval is The best diagnostic threshold with coronary artery diameter is The corresponding specificity and sensitivity were And.<br>In this study, the locations of cat were as follows: left anterior descending coronary artery, left main coronary artery, right coronary artery, left circumflex coronary artery and coronary sinus.<br>The statistical results showed that the left anterior descending coronary artery was the most prone site of thrombosis, while the left circumflex coronary artery and coronary sinus thrombosis were rare.<br>Some of the children had multiple cat, involving multiple coronary arteries at the same time.<br>The average size of thrombus in this group was about With the largest is The smallest is.<br>Coronary angiography and CT angiography in children should not be performed frequently because of the risk. Therefore, transthoracic echocardiography is the most important means of cat detection and follow-up.<br>It should be noted that cat mainly occurs in CAA children, but it can also occur in CAD children. Children with KD complicated with cal should be followed up regularly to prevent cat.<br>For KD patients complicated with CAL, the degree of coronary artery dilatation is a high risk factor for the progression to cat Is the critical value.<br>It is most likely to occur in the left anterior coronary artery.<br>