甲磺酸艾氟替尼原料药呈黄色柱状结晶粉末，具有松堆密度小、粒径分布宽、流

Eftinib mesylate is a yellow columnar crystalline powder with small bulk density, wide particle size distribution, poor fluidity (angle of repose: 51.9 °), and good API stability to humid heat and crystal form . <br>In order to avoid the risk of large tablet weight difference due to poor material flowability, the wet granulation process is preferred.

The agent of efluorothenic acid is a yellow column crystalline powder, with the characteristics of small pine pile density, wide particle size distribution, poor fluidity (rest angle of 51.9 degrees), and API has good stability of the chemical and crystal type of wet heat.<br>In order to avoid the risk that the powder direct pressure plate may be caused by the large difference in weight due to poor material mobility, the wet rule grain process is given priority.

Efetinib mesylate is a yellow columnar crystalline powder, which has the characteristics of small bulk density, wide particle size distribution, poor fluidity (repose angle is 51.9 °), and API has good chemical and crystal stability to damp heat.<br>In order to avoid the risk of large sheet weight difference caused by poor fluidity of materials, the wet granulation process is preferred.