Yes, look forward to treatment, it is B cell lymphocyte degenerative factor, inhibit B cells, in fact, we use a lot of targeted treatment, in the Bellevue monoantigen before we have a very rich experience with ritoxicy monoantigen, so we are still very sure of the effect of targeted drugs, so this is the same, but only selective targeting, that is CD20 antibodies, this is also a relative B cell inhibition point, so based on this we think it is a very new perspective.
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