At present, rare earth elements are widely used in modern science and technology fields such as metallurgy, petrochemical industry, glass ceramics, electronic optical materials, magnetic materials, medicine, etc. During the development and smelting of rare earth resources, due to inadequate supervision, illegal mining, backward technology, and "three wastes" discharge, the pollution of rare earth elements in water and soil, heavy metals and leaching agents around the mining area and rare earth in the atmosphere are relatively serious. Some studies have shown that the intelligence quotient, memory, attention and reasoning ability of children in rare earth mining area are significantly lower than those in the control area, indicating that rare earth has an impact on brain function, revealing that long-term low concentration intake of rare earth may be harmful. Lanthanum (LA) is the most typical and widely used rare earth. Lanthanum can enter human body through blood-brain barrier, damage the ultrastructure of hippocampal and cortical neurons, and then reduce the learning and memory ability of animals.
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