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本研究中，E2F2通过促进细胞周期从G1期到S期的转变以及增强了胰腺癌
本研究中，E2F2通过促进细胞周期从G1期到S期的转变以及增强了胰腺癌细胞的增殖而在胰腺癌中发挥了促癌作用被首次证明了，并且E2F2被证明可以通过上调RRM2及其下游的DCK表达而增强胰腺癌细胞对吉西他滨的化疗抵抗。关键词：胰腺癌 吉西他滨 E2F2介绍：胰腺癌是一种恶性程度极高的恶性肿瘤，胰腺癌患者的五年生存率低于5%，其导致的死亡在癌症相关死亡中居第四位。
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In this study, E2F2 has been demonstrated for the first time in pancreatic cancer by promoting the transition of the cell cycle from G1 phase to S phase and enhancing the proliferation of pancreatic cancer cells. Downstream DCK expression enhances the chemotherapy resistance of pancreatic cancer cells to gemcitabine. <br><br>Keywords: Pancreatic cancer Gemcitabine E2F2 <br>Introduction: <br><br>Pancreatic cancer is a highly malignant malignant tumor. The five-year survival rate of pancreatic cancer patients is less than 5%, and the death caused by it ranks fourth among cancer-related deaths.
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In this study, E2F2 played a cancer-promoting role in pancreatic cancer by promoting cell cycle transitions from G1 to stage S and increasing the proliferation of pancreatic cancer cells, and E2F2 was shown to enhance the chemotherapy resistance of pancreatic cancer cells to Gisithambin by increasing the expression of RRM2 and its downstream DCK.<br><br>Keywords: Pancreatic cancer Gisithabin E2F2.<br>Introduced:<br><br>Pancreatic cancer is a malignant tumor with a five-year survival rate of less than 5%, resulting in the fourth highest number of cancer-related deaths.
正在翻译中..
In this study, E2F2 has been shown to play a role in promoting the cell cycle transition from G1 to s and enhancing the proliferation of pancreatic cancer cells. E2F2 has been shown to enhance the chemoresistance of pancreatic cancer cells to gemcitabine by up regulating the expression of RRM2 and its downstream dCK.<br>Key words: pancreatic cancer, gemcitabine E2F2<br>Introduction:<br>Pancreatic cancer is a highly malignant tumor. The five-year survival rate of pancreatic cancer patients is less than 5%, and the death caused by pancreatic cancer ranks the fourth among cancer-related deaths.<br>
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