大剂量丙种球蛋白联合小剂量醋酸泼尼松治疗川崎病患者的临床效果观察摘要：

Observation of the clinical effect of high-dose gamma globulin combined with low-dose prednisone acetate in the treatment of patients with Kawasaki disease. <br><br>Abstract: Objective: To evaluate the clinical effect of high-dose gamma globulin single dose, shock therapy combined with low-dose prednisone acetate in the treatment of patients with Kawasaki disease; <br><br>Methods: 80 patients with Kawasaki disease were randomly divided into two groups, each with 40 cases. The experimental group received a single dose of high-dose gamma globulin, pulse therapy combined with low-dose prednisone acetate, and the control group received conventional dose gamma globulin treatment Both groups of patients received oral aspirin treatment, and were given symptomatic treatments such as anti-inflammatory, nutritional support, correction of water and electrolyte disorders, and acid-base balance. All patients were admitted to the hospital, 1d, 7d, and 14d after treatment, and in the morning under the basic state Peripheral venous blood was drawn and enzyme-linked immunosorbent assay (ELISA) was used to detect tumor necrosis factor (TNF-a), C-reactive protein (CRP), interleukin 6 (IL-6) and other inflammatory factors; record the two groups of patients after treatment The body temperature dropped to normal, lymph node swelling recovered, hands and feet swelled calf, and mucosal congestion subsided time; comprehensive evaluation of the treatment effect of the two groups of patients. <br><br>Results: After treatment, the experimental group was significantly lower than the control group TNF-a, CRP, IL-6 and other inflammatory factors, the difference was statistically significant (p

The clinical effects of high-dose propylene globulin combined with small-dose acetic acid pernisson in the treatment of patients with Kawasaki disease were observed<br><br>Abstract: Objective: To evaluate the clinical effects of high-dose C-globulin monodose and impact therapy in combination with small doses of acetic acid pernisone in treating patients with Kawasaki disease;<br><br>Methods: 80 patients with Kawasaki disease were randomly divided into two groups of 40 cases, in which the experimental group received a large dose of propylene globulin monoprotein, shock therapy combined with a small dose of pericid acetic acid pernicone treatment, the control group received a conventional dose of propylene globulin treatment, two Group of patients were treated oral with aspirin, and given anti-inflammatory, nutritional support, correction of hydrolyte disorders and acid-base balance and other treatment, all patients were admitted to hospital, after treatment 1d, 7d, 14d, The level of change of inflammatory factors such as tumor necrosis factor (TNF-a), C reaction protein (CRP), leukokin 6 (IL-6) was detected by enzymatic immune adsorption test (ELISA) to extract extrinsic venous blood in the morning basic state;<br><br>Results: The level of inflammatory factors such as TNF-a, CRP and IL-6 decreased significantly in the post-treatment experimental group, and the difference was statistically significant (p).

Clinical effect of high dose gamma globulin combined with small dose prednisone acetate in the treatment of Kawasaki disease<br>Abstract: Objective: To evaluate the clinical effect of high dose gamma globulin single dose, pulse therapy combined with small dose prednisone acetate in the treatment of Kawasaki disease;<br>Methods: 80 patients with Kawasaki disease were randomly divided into two groups, 40 cases in each group. The experimental group received high-dose gamma globulin single dose, pulse therapy combined with low-dose prednisone acetate treatment, while the control group received conventional dose of gamma globulin treatment. Both groups received oral aspirin treatment, and received anti-inflammatory, nutritional support, correction of water and electrolyte disorders and acid-base balance After treatment, peripheral venous blood samples were taken from all patients at the time of admission, 1D, 7d, 14d after treatment. The levels of TNF-a, CRP, IL-6 and other inflammatory factors were detected by enzyme-linked immunosorbent assay (ELISA); the body temperature decreased to normal, lymph node swelling recovered, hands and feet of the two groups were recorded The swelling leg, mucosal congestion subsided time; and the treatment effect of the two groups were comprehensively evaluated.<br>Results: after treatment, the levels of TNF-a, CRP, IL-6 and other inflammatory factors in the experimental group were significantly lower than those in the control group (P<br>