层析柱上柱前水洗的作用为：通过上柱前水洗，检查层析柱设备状态及防止树脂

The function of the pre-column washing of the chromatography column is to check the condition of the chromatography column equipment and prevent the resin from cavitation and fracture due to lack of water inside the resin through the pre-column washing. Deviations occur in the chromatographic column and the column is washed before the column, and the cause is found in time, the fixed rod is repaired, and the pre-column washing regulations are completed, so it has no effect on the product quality; the deviation occurs in the column and the column is washed before the column, and occurs in the equipment During the startup process, no parameter records are generated, so there is no record risk. Through on-site investigation and extraction production line, it is found that the liquid caustic soda pipeline, crude product two-in-one and primary refined product two-in-one material inlet pipeline are each equipped with YYF intelligent float flowmeter, but this type of float flowmeter is without fixed rod Electronic flowmeter, so the possibility of this type of deviation is ruled out.

The function of pre column washing on chromatographic column is to check the state of chromatographic column equipment through pre column washing and prevent resin cavitation and fault due to lack of water inside the resin. The deviation occurred in the pre column washing of chromatographic column, and the cause was found in time, and the fixed rod was repaired to complete the pre column washing regulations, so there was no impact on the product quality; The deviation occurred in the pre column washing on the chromatographic column, and occurred in the process of equipment start-up, so there was no risk of recording. Through on-site investigation of extraction production line, it is found that YYF intelligent rotameter is installed in liquid alkali pipeline, crude product two in one and primary refined product two in one material inlet pipeline of pretreatment post, but this type of rotameter belongs to electronic flowmeter without fixed rod, so the possibility of this type of deviation is ruled out.<br>

The function of pre-column washing on chromatographic column is to check the status of chromatographic column equipment and prevent the phenomenon of resin cavitation and fault caused by water shortage inside the resin. The deviation occurred in the washing before the chromatography column, and the reason was found in time, and the fixed rod was repaired to complete the washing before the column, so it had no impact on the product quality; The deviation occurred in the washing before the column on the chromatographic column, and occurred during the start-up of the equipment, and no parameter record was produced, so there was no risk in recording. Through on-the-spot investigation of the extraction production line, it was found that YYF intelligent float flowmeter was installed in the liquid alkali pipeline, the crude product two-in-one and the primary refined product two-in-one material inlet pipeline of the pretreatment post, but this type of float flowmeter belongs to the electronic flowmeter without fixed rod, so the possibility of this type of deviation was ruled out.