上海艾力斯医药科技有限公司在IND申报阶段，长期稳定性试验被上海艾力斯

<br>During the IND declaration phase, Shanghai Ailisi Pharmaceutical Technology Co., Ltd. has produced a batch of AST2818-141121, AST2818-141208, AST2818-160413, AST2818-161008, AST2818-171018, AST2818- 171209. <br>The accelerated and long-term stability tests were carried out by Jiangsu Ailisi Biomedical Co., Ltd. on the batches AST2818-160616, AST2818-170517, and AST2818-170612 produced by them. <br><br>After the process verification, the influencing factor test was carried out by Zhejiang Ruibo Pharmaceutical Co., Ltd. on the stability research batch CN0190402, and the accelerated and long-term stability tests were carried out on the stability research batches CN0190102, CN0190401, CN0190402 and CN0190403. Sample situation See Table 3.2.S.7-1. <br><br>Shanghai Ellis <br>Jiangsu Ellis Biopharmaceutical Co., Ltd. No. 1 workshop <br>prepares canine long poison preparation. <br>Zhejiang Ruibo Pharmaceutical Co., Ltd. workshop No. 11 <br>two-layer medicinal packaging polyethylene inner bag

Shanghai Ayles Pharmaceutical Technology Co., Ltd.<br>In the IND declaration stage, the long-term stability test was carried out by Shanghai Ayles on its production batch AST2818-141121, AST2818-141208, AST2818-160413, AST2818-161008, AST2818-171018, AST2818-171209.<br>The acceleration and long-term stability test was carried out by Jiangsu Ayles Biopharmaceutical Co., Ltd. on its production batch AST2818-160616, AST2818-170517, AST2818-170612.<br><br>After process verification, the influence factor test was carried out by Zhejiang Rebo Pharmaceutical Co., Ltd. on the stability research batch CN0190402, and the acceleration and long-term stability test was carried out on the stability research batch CN0190102, CN0190401, CN0190402 and CN0190403, the sample situation is shown in Table 3.2.S.7-1.<br><br>Shanghai Ayles<br>1st Workshop, Jiangsu Ayles Biopharmaceutical Co., Ltd.<br>Preparation of dog-length toxic preparations for production<br>Zhejiang Rebo Pharmaceutical Co., Ltd. 11th workshop<br>Two layers of medicinal packaging polyethylene inner bag

Shanghai Ellis Pharmaceutical Technology Co., Ltd<br>In the ind declaration stage, the long-term stability test was carried out by Shanghai Alice on the batches of ast2818-141121, ast2818-141208, ast2818-160413, ast2818-161008, ast2818-171018 and ast2818-171209.<br>The accelerated and long-term stability tests were carried out by Jiangsu Ellis biomedical Co., Ltd. on the batches of ast2818-160616, ast2818-170517 and ast2818-170612.<br>After the process validation, the influencing factor test was carried out by Zhejiang Ruibo Pharmaceutical Co., Ltd. on the stability study batch cn0190402, and the accelerated and long-term stability tests were carried out on the stability study batches cn0190102, cn0190401, cn0190402 and cn0190403. See table 3.2. S.7-1 for the sample situation.<br>Shanghai Ellis<br>No.1 Workshop of Jiangsu Ellis biomedical Co., Ltd<br>Preparation of dog long poison preparation for production<br>Workshop 11 of Zhejiang Ruibo Pharmaceutical Co., Ltd<br>Two layer medical packaging polyethylene inner bag