摘要：器官芯片不仅是一个比较前沿的科学研究方向，而且是一门新兴的多学科

Abstract: Organ chip is not only a relatively cutting-edge scientific research direction, but also an emerging multi-disciplinary scientific research technology, which is of great significance to the development of human health, scientific medical insurance and clinical medical industry. The organ chip is a kind of organ physiological micro-system with the shape and size of the glass slide constructed on the micro-flow control technology chip. It contains important components of the organ micro-environment, such as living organ cells, tissues and organ structures, and biological Shear force, fluid force and mechanical force in the body. It simulates the main functional structure and characteristics of different tissues and organs in vitro. The states and relationships between different organs are used to detect and predict the human body's different responses to different external stimuli or drugs and poisons. It has broad application prospects and research value in the fields of medical research, new drug development, personality therapy, toxicity prediction, and life sciences. From the perspective of different organ chips, the application of organ chips developed in recent years in the construction of physiological models of different human organs, drug development and toxicity monitoring, etc. are introduced, and the future development trend of organ chips is prospected.

Abstract: Organ chip is not only a more cutting-edge scientific research direction, but also a new multidisciplinary scientific research technology, which is of great significance to the development of human health, scientific medical insurance and clinical medical industry. The chip is a kind of device physiological microsystem with the shape and size of a slide, which contains important components of the micro-environment of the organ, such as living organ cells, tissue structure, shearing force, fluid strength and mechanical force in the organism. It simulates the main functional structure and characteristics of different tissue organs in vitro. States and relationships between different organs are used to detect and predict the body's response to different external stimuli or different reactions to drugs and poisons. In medical research, new drug development, personality therapy, toxicity prediction, life science and other fields have broad application prospects and research value. From the perspective of different organ chips, this paper introduces the application of organ chips in different organ physiological model construction, drug research and drug research and toxicity monitoring in human body in recent years, and looks forward to the future development trend of organ chips.

Abstract: organ chip is not only a relatively cutting-edge scientific research direction, but also an emerging multi-disciplinary scientific research technology, which is of great significance to the development of human health, scientific medical insurance and clinical medical industry. Organ chip is a kind of physiological micro system with slide shape and size, which is built on the chip of micro flow control technology. It contains important components of organ microenvironment, such as living organ cells, tissue and organ structure, shear force, fluid force and mechanical force in organism. It simulates the main functional structure and characteristics of different tissues and organs in vitro. The state and relationship between different organs are used to detect and predict the different responses of human body to different external stimuli or drugs and poisons. It has broad application prospects and research value in medical research, new drug development, personality therapy, toxicity prediction, life science and other fields. From the perspective of different organ chips, this paper introduces the application of organ chips developed in recent years in the construction of physiological models of different human organs, drug research and development and toxicity monitoring, and looks forward to the future development trend of organ chips.<br>